Alzheimer's Disease: Optimizing Drug Development Strategies

Alzheimer2s Disease: The Problem and the Search for Solutions. Diagnosis: Procedures and Criteria. Basic and Clinical Alzheimer2s Disease Models. Central End-Organ Responses: Structural and Functional Measures. Peripheral End-Organ Responses: Red Blood Cell Cholinesterase and Salivary Amylase. Neuropsychological End-Organ Responses: The Computerized Neuropsychological Test Battery. Subject Selection and Sample Size. Age as a Factor in Drug Development. Finding the Dose: The Bridging Study. Concluding Remarks. Index.John J. Sramek is the author of 'Alzheimer's Disease: Optimizing Drug Development Strategies', published 1994 under ISBN 9780471951452 and ISBN 0471951455.