Purification of Laboratory Chemicals

Purification of Laboratory Chemicals Fifth Edition Wilfred L.F. Armarego, John Curtin School of Medical Research, Australian National University, Canberra Christina L.L. Chai, Department of Chemistry, Australian National University, Canberra ·The only complete source that covers the purification of laboratory chemicals that are commercially available in such an easy-to-use format ·Provides purification procedures for commercially available chemicals and biochemicals ·Includes an extremely useful compilation of ionisation constants Now in its fifth edition, Purification of Laboratory Chemicals continues to provide laboratory scientists with a manual for purifying and increasing the purity of modern commercially available chemical substances. The authors have written and revised six chapters that describe the aspects of purification and properties of chemical substances. In addition to detailing physical methods and procedures such as crystallization, distillation, chromatography, etc., the authors also address chemical methods and procedures used in purification including conversion to specific derivatives or complexes and regeneration of the original material in a much-purified form. The book also outlines recent developments in synthesis (e.g. combinatorial chemistry, solid support chemistry, fluorous chemistry) and the corresponding purification procedures that will provide many of the commercially supplied chemical substances in years to come. Additionally, interesting perspective about the future of purification is provided by the authors, based on their years of experience. The bulk of the book contains purification procedures (taken from the literature) of individual entries for commercially available organic compounds, inorganic and metal-organic compounds, and biochemical and related compounds respectively. The entries are accessible in alphabetical order, and in most cases synonymous names and/or abbreviations are included as well as the CAS (Chemical Abstracts Service) Registry Numbers. The physical properties have been entered, such as the molecular weight, melting and boiling points, and specific rotations if substances are optically active. Rapid purification procedures for common solvents have also been included after the respective extensive procedures. New to this edition, the ionisation constants in the form of pK have been entered for ionisable compounds. These are followed by procedures, used to purify the substances, in most cases to analytical purity. An index of CAS Registry Numbers with the respective page numbers of the entries has been added as well, making it easy to locate any substance irrespective of which chapter it is in, and also rapidly telling the reader whether there is a purification procedure for that substance in this book.Armarego, W. L. F. is the author of 'Purification of Laboratory Chemicals', published 2003 under ISBN 9780750675710 and ISBN 0750675713.