Biochemistry and Physiology of the Skin - Lowell A. Goldsmith

There have been rapid advances in the molecular biology of the skin since the first appearance of this acclaimed work. The genes for several of the structural and regulatory proteins in the epidermis and dermis have been cloned and their regulation is being characterized. Understanding the skin at the genetic level has yielded new insights into skin physiology and these are presented in the Second Edition. The section on the immune system, both its afferent arm including the Langerhans cell, and its efferent functions including the interleukins, has been greatly expanded. A new section on the neurobiology of skin discusses cell-to-cell communication and the expanded role of the Merkel cell, among other topics. Growth factors have increasing significance in normal control of skin growth, psoriasis, and neoplasia; these factors and their implications are discussed extensively in the new edition. Like the first edition, this book is rich in data, profusely illustrated with light and electron micrographs, and heavily referenced. It is the first choice as a reference work for skin researchers throughout the world and the prime source for basic science education of dermatologists and dermatology trainees.Goldsmith, Lowell A. is the author of 'Biochemistry and Physiology of the Skin - Lowell A. Goldsmith' with ISBN 9780195056129 and ISBN 0195056124.