Protein Purification : Design and Scale up of Downstream Processing

Protein purification describes general techniques useful for translating industrial bioprocesses from laboratory to any larger scale. This book is directed towards readers with both biochemistry and engineering backgrounds. One of the challenges in this field is the integration of engineering and biology in the design of process systems. The work is designed to facilitate the interaction between these two groups. Backed by practical examples, case studies and extensive literature references, the book offers primary value for technologists, whose specialty is the design and optimization of fermentation and cell culture processes for downstream recovery of protein and peptide products. Of use to researchers, production operators and students, Dr. Wheelwright's strategy sets forth practical guidelines and shows how to define product specifications and establish design strategies, specify unit operations, scale up unit operation recovery techniques, and optimize purification processes.Wheelwright, Scott M. is the author of 'Protein Purification : Design and Scale up of Downstream Processing', published 1991 under ISBN 9780195209136 and ISBN 0195209133.