The top-selling short course book for undergraduates and medical studentsNow in its Sixth Edition, this widely acclaimed textbook has been updated and revised to incorporate new findings in the field of immunology. Providing a concise yet thorough introduction to the subject, this text continues to provide complete coverage of all key topics in modern immunology without overburdening the reader with excessive detail or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations-many brand- new to this edition.Immunology: A Short Course, Sixth Edition includes completely rewritten or new coverage of key topics such as: toll-like receptors, their ligands, and intracellular activation pathways; development of T-cell subsets; mucosal immunity; the role of activation-induced cytidine deaminase (AID) in somatic hypermutation and class switch recombination; the autoimmune regulator (AIRE) gene in self-tolerance and autoimmunity; and complement activation pathways.Each chapter is complemented with bulleted summaries and review questions with detailed answers. The book also contains an extensive glossary. Written in a clear, user-friendly style, this text is suitable for integrated courses that cover microbiology, immunology, and pathology, as well as focused immunology courses. An updated Web site provides relevant online resources including downloadable figures and tables used in the text.Richard Coico is the author of 'Immunology: A Short Course', published 2009 under ISBN 9780470081587 and ISBN 0470081589.