Comments: All orders ship SAME or NEXT business day! Ships with Tracking Number! May not contain Access Codes or Supplements. 100% Satisfaction Guaranteed!
30-day money back guarantee
Matern, Siegfried, Boyer, J. L., Keppler, D.
There has been a tremendous amount of scientific progress in our understanding of the molecular mechanisms of transport processes in the liver within the last few years. Cloning of various members of organic anion and cation transporters has provided the necessary tools to study their regulation under physiological and pathophysiological conditions and has advanced our knowledge about bile formation. Mutations of various hepatic organic anion transporters have been identified in humans as hereditary defects leading to the heterogenous syndrome of progressive familial intrahepatic cholestasis (PFIC). Various mouse models including knockout animals have given us the opportunity to gain insight into lipid transport by the liver and the genetics of cholesterol gallstone formation. The physiology of bile duct cells and the molecular mechanisms leading to various cholangiopathies have been a main scientific focus in hepatology in recent years. Drug targeting to the liver by hepatic organic anion transporters represents an attractive way of selective delivery of pharmaceutical agents in humans. Ursodeoxycholic acid is successfully used in the treatment of patients with chronic cholestatic liver disease and major advances have been made in understanding its mode of action in liver and bile duct cells. This book, the proceedings of the Falk Workshop held in Aachen, Germany, on 25-26 January 2001, contains chapters on all important aspects of biliary transport by well-known experts in this field. It is an essential resource for new developments in the field of biliary transport, both in basic science and clinical medicine.Matern, Siegfried is the author of 'Hepatobiliary Transport From Bench to Bedside' with ISBN 9780792387718 and ISBN 0792387716.
With our dedicated customer support team, 30-day no-questions-asked return policy, and our price match guarantee, you can rest easy knowing that we're doing everything we can to save you time, money, and stress.
Book condition guidelines
New (perfect condition)
Pages are clean and are not marked by notes, highlighting or fold.
Like new (excellent condition)
Pages are clean and are not marked by notes, highlighting or folds.
Very good (good condition)
Pages are intact and may have minimal notes and/or highlighting or folds.
Good (clean condition)
All pages and the cover is intact. The spine may show signs of wear. Pages include notes and/or highlighting.
Acceptable (readable condition)
All pages and the cover is intact. Pages include considerable notes in pen or highlighter, but the text is not obscured.
How do rentals work?
Save up to 90% on the largest selection of textbook rentals in the business. We have the lowest prices - guaranteed.
Choose between standard or expedited shipping to make sure that your textbooks arrive in time for class.
Return for free!
When your books are due, just pack them up and ship them back. And don't worry about shipping - it's absolutely free!