516020
9780195039221
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This text uses a case-study format to relate the fundamentals of biochemistry to the diagnosis and treatment of disease. Clinical descriptions of selected diseases include explanations of their molecular mechanisms and the associated chemical and enzymatic alterations in tissues and body fluids. Thirty carefully selected cases demonstrate important biochemical principles. Each study follows a consistent format: a case report presents the history, physical findings and relevant laboratory data of the index case, including photographs of X-rays and other illustrations; the diagnosis includes structural formulae of enzyme-catalyzed reactions and provides the most definitive method for confirming the diagnosis; a discussion of the biochemical perspective gives a detailed account of the normal processes or reactions that are involved, along with the mechanism responsible for the disease; therapeutic options are presented and the the typical prognosis is described; several questions test the reader's understanding; and the bibliography lists important reviews and key articles. Illustrating the intimate links between basic medical sciences and disease, this text presents biochemistry in a manner that is accessible and relevant to students interested in patient care.Glew, Robert H. is the author of 'Clinical Studies in Medical Biochemistry' with ISBN 9780195039221 and ISBN 019503922X.
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