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First Signals: The Evolution of Multicellular Development






Pub Date: 
Publisher:  Princeton University Press
Summary: The enormous recent success of molecular developmental biology has yielded a vast amount of new information on the details of development. So much so that we risk losing sight of the underlying principles that apply to all development. To cut through this thicket, John Tyler Bonner ponders a moment in evolution when development was at its most basic--the moment when signaling between cells began. Although multicellul...arity arose numerous times, most of those events happened many millions of years ago. Many of the details of development that we see today, even in simple organisms, accrued over a long evolutionary timeline, and the initial events are obscured. The relatively uncomplicated and easy-to-grow cellular slime molds offer a unique opportunity to analyze development at a primitive stage and perhaps gain insight into how early multicellular development might have started.Through slime molds, Bonner seeks a picture of the first elements of communication between cells. He asks what we have learned by looking at their developmental biology, including recent advances in our molecular understanding of the process. He then asks what

Bonner, John Tyler is the author of First Signals: The Evolution of Multicellular Development, published 2001 under ISBN 9780691070377 and 0691070377. One First Signals: The Evolution of Multicellular Development textbook is available for sale on ValoreBooks.com, or buy new starting at $140.39.
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First Signals: The Evolution of Multicellular Development

ISBN-13: 9780691070377

ISBN: 0691070377

Pub Date:
Publisher: Princeton University Press
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