Cilia and Mucus From Development to Respiratory Defense

9780824704414

082470441X

This book details advances in research regarding cilia, mucus, and mucociliary clearance, examining changes in mucus expression and goblet cell metaplasia, and assessing the ability of the mucociliary system to respond to abnormalities. Recognizes that cilia and dynein arms play pivotal roles in developing mammalian embryos! Examines the role of genetics in normal and abnormal ciliary function! Discussing scientific fundamentals, current diagnostic techniques, and clinically tested treatments, Cilia and Mucus · analyzes the regulation of ciliary waves at the cellular level · considers irregularities of upper and lower airways and cilia in systems of the body · explores potential modulators of airway mucin secretion · proposes a novel therapy for airway hypersecretion due to the epidermal growth factor cascade · clarifies gamma camera imaging to measure mucociliary clearance · describes the effect of purinergic receptors and dry powder mannitol on airway passages · and more! With contributions from over 100 international researchers and clinicians, and containing over 1300 references, drawings, photographs, tables, and equations, Cilia and Mucus is a unique single-source reference for pulmonologists, physiologists, immunologists, allergists, otolaryngologists, pediatricians, microbiologists, basic scientists, and graduate and medical school students in these disciplines.