Cancer of the Prostate

9780824788636

082478863X

This comprehensive, clinically oriented text covers the recent developments concerning the epidemiology, aetiology, pathology, diagnosis and management of prostate cancer - ranging from the latest reports of surveillance with no immediate treatment for selected patients to early aggressive therapy for advanced cancer with total androgen blockade.;Written by more than 30 internationally recognized experts, Cancer of the Prostate: examines current understanding of the histopathology and nuclear ploidy as they pertain to the prognosis of prostate cancer; discusses the implications of various possible screening procedures like digital rectal examination, PSA and transrectal prostatic ultrasound; addresses the controversies surrounding the true impact of screening on survival of prostate cancer; explores pragmatic concerns about possible over-treatment of latent cancers; elaborates the newer minimally invasive technique of laparoscopic lymph nodal staging; describes radical extirpative surgeries for localized disease by the retropubic as well as the resurgent perineal approach; details external beam radiation therapy with newer additive measures like hyperthermia; explains recently refined intersitial radioactive seed implantation techniques for brachytherapy; and elucidates the newer chemotherapeutic approaches with combined chemoendocrine treatment and the prospects of the latest growth factor inhibitors in the management of hormone refractory metastatic disease.;Containing over 1100 references for further in-depth study of particular topics, Cancer of the Prostate is a resource for urologists, oncologists, surgeons, radiologists, primary care physicians, and medical students in these disciplines.