Analysis of Neuronal Microcircuits and Synaptic Interactions

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0444812318

This volume of the Handbook of Chemical Neuroanatomy describes the techniques used to study the connectivity of chemically defined neurons at the cellular level. Among areas dealt with are the most recent developments in light microscopy and electron microscopy, and the applications to specific subjects of chosen combinations of techniques to demonstrate how elegantly and powerfully they can be applied. As the fiber connections of the brain become increasingly accurately mapped, the desire to understand the instrinsic circuits of these populations of neurons, including their morphology, neurotransmitters, neuromodulators, receptors and their physiology, will grow. It is this desire for knowledge the authors are attempting to stimulate by presenting a comprehensive technical book on most of the currently used and theoretically possible combinations of anatomical, physiological and immunocytochemical methods for the study of neuronal micricircuits and synaptic interaction. An indispensible guide and "laboratory benchtool".